Serum anti-candida albicans antibodies in candidal and non-candidal vaginitis

The agglutination, immunodiffusion and immune adherence tests were performed on sera from 60 women with clinically diagnosed vaginitis. Candida albicans was isolated from the vaginal discharge of 36 of them (Group 1) and not from the other 24 (Group 2). Fifty eight patients reacted positively in the agglutination test. No differentiation could be made between the two groups on the basis of this test (number of positive sera and height of titer). No antibodies could be detected by the immunodiffusion test (except for one positive serum). The immune adherence test demonstrated a difference between the two groups, which was expressed both in the total of positive reacting sera and in titer of antibodies.