High-resolution cortical mapping within and across the central sulcus using 1024-electrode micro-electrocorticography...

Area of Science:

• Neurosurgery
• Neurophysiology
• Biomedical Engineering

Background:

• Electrocorticography (ECoG) is vital for neurosurgical mapping of the central sulcus.
• Standard ECoG arrays offer limited resolution (millimeters) for precise localization.
• Accurate central sulcus identification is crucial for interventions near motor and sensory cortices.

Purpose of the Study:

• To evaluate the feasibility and utility of high-resolution micro-ECoG (µECoG) for sensorimotor mapping within the central sulcus.
• To compare µECoG mapping resolution with standard ECoG techniques.
• To demonstrate the application of µECoG in a clinical neurosurgical setting.

Main Methods:

• A patient underwent tumor resection involving the central sulcus.
• Standard ECoG was used for initial localization.
• High-resolution µECoG arrays (2048 electrodes) were applied across the central sulcus.
• Augmented reality imaging overlay was utilized for surgical guidance.

Main Results:

• µECoG successfully identified a high-resolution phase-reversal contour across the central sulcus.
• The phase reversal was detected at a resolution of approximately 400 microns.
• Electrophysiology within the dissected central sulcus was visualized using µECoG.

Conclusions:

• µECoG provides unprecedented resolution for sensorimotor mapping within the central sulcus.
• This high-resolution mapping technique enhances precision for neurosurgical tumor resections.
• µECoG holds potential for advancing brain-computer interfaces and other neurosurgical applications.