Related Experiment Video

Updated: Feb 11, 2026

Assessing the Coherence of Parents' Short Narratives Regarding their Child Using the Five-Minute Speech Sample Procedure
07:56

Assessing the Coherence of Parents' Short Narratives Regarding their Child Using the Five-Minute Speech Sample Procedure

Published on: September 19, 2019

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Subcortical regional volume vulnerability linked to child neglect without other forms of maltreatment

Natasha Y S Kawata1, Takashi X Fujisawa2, Akiko Yao3

  • 1Research Center for Child Mental Development, University of Fukui, Fukui 910-1193, Japan; Department of Psychology, University of Western Ontario, London N6A 5C2, Canada.

Brain Research Bulletin
|February 9, 2026
PubMed

Insights

Child neglect can alter brain development, specifically the corpus callosum (CC) in boys. This CC region

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Child Psychiatry

Background:

  • Child neglect during development is linked to long-term adverse health and mental health outcomes.
  • The corpus callosum (CC) is crucial for interhemispheric communication and brain development.

Purpose of the Study:

  • To investigate if child neglect is associated with alterations in corpus callosum (CC) morphology.
  • To explore the neural mechanisms linking neglect to psychosocial characteristics in children.

Main Methods:

  • T1-weighted magnetic resonance imaging (MRI) was used to assess brain morphology.
  • Compared CC morphology in Japanese children with a history of neglect (n=22) and non-maltreated children (n=66).

Main Results:

  • Boys exposed to neglect showed significantly greater middle anterior CC (CC2) volume compared to non-neglected boys.
  • Increased CC2 volume correlated positively with hyperactivity-inattention scores in both sexes.

Conclusions:

  • Child neglect may have sex-specific effects on CC development.
  • CC morphology alterations are associated with psychosocial functioning in neglected children, highlighting neurodevelopmental consequences.

Keywords:
AttentionCorpus callosumHyperactivityMRI analysisNeglectNeurodevelopmentSex differences

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