Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nuclear Fusion02:45

Nuclear Fusion

33.9K
The process of converting very light nuclei into heavier nuclei is also accompanied by the conversion of mass into large amounts of energy, a process called fusion. The principal source of energy in the sun is a net fusion reaction in which four hydrogen nuclei fuse and ultimately produce one helium nucleus and two positrons.
A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
33.9K
Glaucoma: Overview01:25

Glaucoma: Overview

1.4K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.4K
Bacterial Transformation01:33

Bacterial Transformation

60.1K
In 1928, bacteriologist Frederick Griffith worked on a vaccine for pneumonia, which is caused by Streptococcus pneumoniae bacteria. Griffith studied two pneumonia strains in mice: one pathogenic and one non-pathogenic. Only the pathogenic strain killed host mice.
Griffith made an unexpected discovery when he killed the pathogenic strain and mixed its remains with the live, non-pathogenic strain. Not only did the mixture kill host mice, but it also contained living pathogenic bacteria that...
60.1K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

1.0K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.0K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.3K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.3K
Nursing Diagnosis01:22

Nursing Diagnosis

4.2K
Following assessment, a nursing diagnosis is the next step in the nursing process. It begins after the nurse has collected and recorded the patient data. The purpose of diagnosing is to identify how the client responds to actual or potential health processes, identify factors that bestow or that cause health problems, the etiologies, and identify resources or strengths the individual, group, or community can draw on to prevent or resolve problems.
The nursing diagnosis focuses on evidence-based...
4.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cloud-enabled hybrid structural equation modeling and artificial neural network framework for energy-efficient green buildings.

Scientific reports·2026
Same author

HYDRA-XAI dual-backbone disaster scene recognition using ResNet50-Swin transformer feature fusion, explainable evidence, and an operational recommender.

Scientific reports·2026
Same author

Quantified LIME explainability and class-specific dual-branch trust calibration for safety-critical road-scene perception in autonomous navigation.

Scientific reports·2026
Same author

Quantum-inspired optimization of transformer-capsule networks for accurate brain tumor segmentation and classification.

Scientific reports·2026
Same author

ColoXAI-RecomNet: Explainable Recommender Framework for Colorectal Cancer Classification Using Integrated CNN Ensemble and LIME Interpretability.

Journal of imaging informatics in medicine·2026
Same author

Infrared thermography for the diagnosis and monitoring of Raynaud's phenomenon: current evidence and future directions.

Reumatologia·2026

Related Experiment Video

Updated: Feb 11, 2026

4-Dimensional Imaging of Zebrafish Optic Cup Morphogenesis
07:26

4-Dimensional Imaging of Zebrafish Optic Cup Morphogenesis

Published on: May 26, 2021

3.9K

SwinCup-DiscNet: A fusion transformer framework for glaucoma diagnosis using optic disc and cup features.

Rajitha Chilukuri1, P Praveen2, Ranjith Kumar Gatla3

  • 1School of Computer Science and Artificial Intelligence, SR University, Warangal, Telangana, 506371, India.

Scientific Reports
|February 9, 2026
PubMed
Summary

This study introduces SwinCup-DiscNet, a novel pipeline for early glaucoma detection. It effectively integrates optic disc/cup segmentation and deep learning features for accurate diagnosis, outperforming existing methods.

Keywords:
Attention U-NetCup-to-disc ratioDeep learningGlaucomaOptic cupSwin transformer

More Related Videos

Induction and Diagnosis of Tumors in Drosophila Imaginal Disc Epithelia
08:14

Induction and Diagnosis of Tumors in Drosophila Imaginal Disc Epithelia

Published on: July 25, 2017

15.8K
Fabricating Optical-quality Glass Surfaces to Study Macrophage Fusion
08:50

Fabricating Optical-quality Glass Surfaces to Study Macrophage Fusion

Published on: March 14, 2018

7.6K

Related Experiment Videos

Last Updated: Feb 11, 2026

4-Dimensional Imaging of Zebrafish Optic Cup Morphogenesis
07:26

4-Dimensional Imaging of Zebrafish Optic Cup Morphogenesis

Published on: May 26, 2021

3.9K
Induction and Diagnosis of Tumors in Drosophila Imaginal Disc Epithelia
08:14

Induction and Diagnosis of Tumors in Drosophila Imaginal Disc Epithelia

Published on: July 25, 2017

15.8K
Fabricating Optical-quality Glass Surfaces to Study Macrophage Fusion
08:50

Fabricating Optical-quality Glass Surfaces to Study Macrophage Fusion

Published on: March 14, 2018

7.6K

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Artificial Intelligence

Background:

  • Glaucoma is a leading cause of irreversible blindness, characterized by optic nerve head (ONH) damage.
  • Early detection of glaucoma is crucial for preventing vision loss.

Purpose of the Study:

  • To develop and evaluate a novel fusion transformer pipeline for effective glaucoma screening.
  • To integrate optic disc/cup segmentation with feature-based analysis for enhanced diagnostic accuracy.

Main Methods:

  • A U-Net with an attention mechanism was used for Optic Disc (OD) and Optic Cup (OC) segmentation.
  • Spectral shape descriptors were employed to calculate the Vertical Cup-to-Disc Ratio (CDR).
  • Swin Transformer encoder extracted fundus image features, and a probabilistic fusion method merged CDR and deep learning features for classification.

Main Results:

  • The SwinCup-DiscNet framework demonstrated superior performance compared to traditional CNN-based models and segmentation-only methods across three public datasets (LAG, ACRIMA, DRISTHI-GS).
  • The model achieved high accuracy, DSC IoU, F1-score, and low Cup-to-Disc Ratio Mean Absolute Error (CDR MAE).

Conclusions:

  • SwinCup-DiscNet is a robust, reliable, and clinically interpretable tool for early glaucoma detection.
  • The proposed framework shows significant potential as an effective clinical tool in real-world settings.