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Updated: Feb 11, 2026

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness
Published on: March 18, 2022
Subchondral bone abnormalities in the knee: imaging techniques, regional anatomy, and pathology
Eddy D Zandee van Rilland1, Robert D Boutin2, Kathryn J Stevens2
1Department of Radiology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA, 94305, USA. ezandee@stanford.edu.
None:
The subchondral bone is an integral structural component of the knee with key roles in shock absorption and load distribution. Injuries to the subchondral bone, which may occur secondary to various etiologies including trauma, degenerative disease, or repetitive overuse, are commonly encountered in clinical practice. Radiographs are generally performed as an initial imaging test to identify any gross osseous abnormalities. However, magnetic resonance imaging (MRI) is the modality of choice for the accurate evaluation and characterization of subchondral bone abnormalities, such as osseous contusion, insufficiency fracture, stress response, osteonecrosis, arthropathy, and neoplasm. Similarly, osteochondral derangements, including osteochondral fracture and osteochondritis dissecans, are also accurately identified with MRI. Therefore, knowledge of the MRI appearance of both normal anatomy and derangements of the subchondral bone are necessary for accurate diagnosis. This article aims to provide a review of the imaging features of subchondral bone abnormalities in the knee, highlighting key diagnostic findings and recommended practices in radiologic terminology and reporting.
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