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Updated: Feb 11, 2026

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
Published on: June 6, 2025
Local Anesthetic Transperineal Prostate Biopsy: Does It Affect Uroflowmetry Results
İsa Dağlı1, Muhammed Zübeyr Canbolat1, Tuncel Uzel1
1Department of Urology, University of Health Sciences Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey.
Transperineal prostate biopsy (TP-Bx) under local anesthesia shows mild, temporary effects on voiding function. Acute urinary retention (AUR) risk is lower than anticipated, supporting TP-Bx as a safe diagnostic option.
Area of Science:
- Urology
- Oncology
- Diagnostic Procedures
Background:
- Transperineal prostate biopsy (TP-Bx) offers reduced infection risk and improved cancer detection.
- Local anesthesia for TP-Bx provides clinical and economic benefits.
- Acute urinary retention (AUR) is a potential post-procedure complication.
Purpose of the Study:
- To assess the impact of TP-Bx under local anesthesia on patient voiding function.
- To evaluate changes in uroflowmetry parameters post-TP-Bx.
Main Methods:
- Prospective observational study of 74 patients undergoing TP-Bx.
- Uroflowmetry assessed pre- and post-procedure, measuring maximum (Qmax) and average (Qave) flow rates, voided volume (Vv), and post-void residual (PVR).
Main Results:
- Significant reductions observed in Qmax and Qave post-TP-Bx (p < 0.001).
- Post-void residual (PVR) increased significantly post-procedure (p < 0.001).
- Observed changes in voiding parameters were mild and did not necessitate catheterization.
Conclusions:
- TP-Bx under local anesthesia demonstrates a lower-than-expected risk of AUR.
- The procedure is a safe and effective diagnostic approach for prostate cancer.
- Experience enhances the safety profile of TP-Bx.
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