Early-Onset Myocardial Infarction in Adults Under 45: A Review of Five Cases

Myocardial infarction (MI) in individuals younger than 45 years is uncommon but carries significant clinical and psychosocial implications. Its presentation challenges traditional assumptions regarding cardiovascular risk and necessitates tailored approaches to diagnosis and management. We conducted a retrospective analysis of five patients aged <45 years admitted to a local hospital in New York with confirmed MI. Data included comorbidities, imaging, laboratory results, angiographic findings, and treatment modalities. Early-onset MI occurred predominantly in males, most of whom exhibited conventional risk factors. Coronary angiography revealed both single- and multi-vessel disease. Follow-up data were incomplete, with two patients lost to follow-up. These findings highlight the importance of recognizing conventional risk factors in younger populations and emphasize the need for individualized long-term management strategies.