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Updated: Feb 11, 2026

Synthesis of Keratin-based Nanofiber for Biomedical Engineering
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Structure-Guided Engineering of KshA Yields a High-Performance 9α-Hydroxylase for Synthesis of 9α-OH-AD

Yanmei Dai1,2, Dongchang Sun2, Qingyu Zhang1

  • 1College of Pharmaceutical Science, Zhejiang Key Laboratory of Green Manufacturing Technology for Chemical Drugs, Zhejiang University of Technology, Hangzhou 310014, China.

ACS Synthetic Biology
|February 10, 2026
PubMed

Keywords:
9α-hydroxy-4-androstene-3,17-dione9α-hydroxylasedirected evolutionfed-batch transformationmolecular dynamics simulationsemirational design

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