VISULYZE: A Novel Nomogram Tool for Optimizing Refractive Outcomes in SMILE Surgery

Area of Science:

• Ophthalmology
• Refractive Surgery
• Biomedical Engineering

Background:

• Small Incision Lenticule Extraction (SMILE) is a popular refractive surgery procedure.
• Accurate nomograms are crucial for optimizing SMILE surgical outcomes.
• VISULYZE is a novel software platform designed for personalized nomogram generation in refractive surgery.

Purpose of the Study:

• To evaluate the efficacy and safety of the VISULYZE nomogram technique in SMILE surgery.
• To compare the refractive outcomes achieved with VISULYZE-generated nomograms versus traditional nomograms.
• To assess the impact of VISULYZE on refractive prediction accuracy in SMILE procedures.

Main Methods:

• A prospective, nonrandomized, controlled study was conducted.
• VISULYZE software was used to create a nomogram based on ideal eye examples.
• Two groups were compared: SMILE 3.0 (traditional nomogram) and SMILE 4.0 (VISULYZE nomogram).
• Patient outcomes were monitored for 3 months, assessing visual acuity, refractive error, and aberrations.

Main Results:

• The VISULYZE nomogram (SMILE 4.0 group) showed significantly higher efficacy (efficacy index 1.11 vs. 1.06) compared to the traditional nomogram (SMILE 3.0 group).
• Refractive error predictability was superior with VISULYZE: 97% within ±0.50 D versus 81% for the traditional method.
• No significant differences in safety outcomes or higher-order aberrations were observed between the groups.

Conclusions:

• The VISULYZE nomogram provides comparable safety to traditional methods while significantly enhancing efficacy in SMILE surgery.
• VISULYZE technology improves the accuracy of refractive outcome prediction for SMILE procedures.
• This advanced nomogram technique represents a valuable advancement for refractive surgeons performing SMILE.