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Diagnostic Axillary US: How Indication and Breast Cancer Status Impact Diagnostic Outcomes
Howard Z Yan1, Tie Liang1, Wendy B DeMartini1
1Department of Radiology, Stanford University Medical Center, Stanford, CA, USA.
Axillary ultrasound (AxUS) findings vary significantly based on breast cancer status and examination reason. Metastatic lymph nodes in women without breast cancer exhibit distinct sonographic features, necessitating careful interpretation.
Area of Science:
- Radiology and Imaging
- Oncology
- Diagnostic Ultrasound
Background:
- Axillary ultrasound (AxUS) is crucial for evaluating lymph node (LN) status.
- Understanding how breast cancer status and examination indication influence AxUS findings is essential for accurate diagnosis.
Purpose of the Study:
- To investigate the impact of examination indication and breast cancer status on LN metastasis prevalence.
- To analyze performance indices and sonographic features of metastatic LNs in AxUS.
Main Methods:
- Retrospective analysis of 2156 AxUS examinations in 1719 women.
- Data collection on indication, breast cancer status, and imaging results.
- Comparison of AxUS performance indices and LN characteristics using statistical analysis.
Main Results:
- Overall LN metastases prevalence was 1.7%.
- Highest prevalence (24.1%) observed in AxUS for treatment planning.
- Metastatic LNs in women without breast cancer showed larger cortices, absent hila, and abnormal shapes.
Conclusions:
- AxUS interpretation requires consideration of examination indication and patient's breast cancer status.
- Sonographic features of LN metastasis differ between women with and without breast cancer.
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