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FedGSCA: Medical Federated Learning With Global Sample Selector and Client Adaptive Adjuster Under Label Noise
IEEE Journal of Biomedical and Health Informatics
|February 10, 2026
Summary
Federated Learning (FL) faces challenges with noisy medical data. Our FedGSCA framework enhances robustness by aggregating noise knowledge and adaptively adjusting client training, outperforming existing methods in complex noise scenarios.
Area of Science:
- Artificial Intelligence
- Medical Imaging
- Machine Learning
Background:
- Federated Learning (FL) enables collaborative medical image classification while protecting data privacy.
- Label noise from data variability causes instability and performance degradation in FL models.
- Current FL methods struggle with heterogeneous noise and imbalanced medical data.
Purpose of the Study:
- To propose FedGSCA, a novel framework to enhance robustness in noisy medical FL.
- To address noise heterogeneity and improve global model stability.
- To mitigate the impact of noisy data and prevent overfitting in local training.
Main Methods:
- FedGSCA utilizes a Global Sample Selector to aggregate noise knowledge across clients.
- A Client Adaptive Adjustment (CAA) mechanism is developed, incorporating adaptive pseudo-labeling and Robust Credal Labeling Loss.
- CAA dynamically adjusts to class distributions, includes minority samples, and manages noisy labels by considering multiple plausible labels.
Main Results:
- FedGSCA was evaluated on real-world colon slides and synthetic medical datasets under diverse noise conditions.
- The framework demonstrated superior performance compared to state-of-the-art methods, particularly in extreme and heterogeneous noise scenarios.
- FedGSCA significantly improved model stability and handling of complex noise.
Conclusions:
- FedGSCA offers a robust solution for noisy medical federated learning.
- The proposed framework effectively handles noise heterogeneity and data imbalance.
- FedGSCA is well-suited for real-world medical FL applications requiring high accuracy and stability.
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