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Unlike ethane and propane that have only two major conformations, butane has more than two conformers. The staggered form of butane in which the bulky methyl groups on the two carbons are placed on opposite sides, that is, at a dihedral angle of 180°, is the lowest energy, most stable form — called the anti conformer. This conformation is stabilized due to the absence of steric repulsion between the largely spaced out methyl groups. The other two staggered conformations are...
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Adolf von Baeyer attempted to explain the instabilities of small and large cycloalkane rings using the concept of angle strain — the strain caused by the deviation of bond angles from the ideal 109.5° tetrahedral value for sp3  hybridized carbons. However, while cyclopropane and cyclobutane are strained, as expected from their highly compressed bond angles, cyclopentane is more strained than predicted, and cyclohexane is virtually strain-free. Hence, Baeyer’s theory that...
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Related Experiment Video

Updated: Feb 12, 2026

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ReGrid: A Highly Conformable and Ultrasound Transparent Patch for HD-sEMG Detection.

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    This study introduces ReGrid, a novel dry electrode grid for high-density electromyography (HD-sEMG). It is skin-conformable and ultrasound-transparent, enabling simultaneous HD-sEMG and ultrasound imaging without signal interference.

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    Area of Science:

    • Biomedical Engineering
    • Neuroscience
    • Medical Imaging

    Background:

    • High-density electromyography (HD-sEMG) requires reliable electrode-skin contact.
    • Integrating HD-sEMG with ultrasound imaging presents challenges due to probe and electrode interference.

    Purpose of the Study:

    • To develop and validate a novel dry electrode grid (ReGrid) for HD-sEMG that is highly conformable and ultrasound-transparent.
    • To assess the feasibility of simultaneous HD-sEMG and ultrasound acquisition using ReGrid.

    Main Methods:

    • Fabrication of a thin-film polyurethane membrane with inkjet-printed silver electrodes and traces.
    • Mechanical conformability and ultrasound transparency testing.
    • In-vivo evaluation on tibialis anterior muscle, recording HD-sEMG signals with and without an ultrasound probe.

    Main Results:

    • ReGrid demonstrated excellent conformability to curved surfaces and complete ultrasound transparency without artifacts.
    • Low and stable electrode-skin impedance with noise levels comparable to gel-based electrodes.
    • Simultaneous HD-sEMG and ultrasound acquisition showed no significant impact on signal quality, conduction velocity, or decomposition outcomes.

    Conclusions:

    • ReGrid is a viable technology for combined HD-sEMG and ultrasound applications.
    • The electrode's properties enable novel integrated imaging and electrophysiological assessments.
    • This facilitates advanced research in areas like 3D and panoramic ultrasound integrated with HD-sEMG.