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A pilot study found that a web-based app supporting opioid tapering showed high patient retention and acceptability. However, low enrollment and app usage indicate a need for modified recruitment strategies for future trials.

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Area of Science:

  • Pain Management
  • Digital Health
  • Behavioral Therapy

Background:

  • Long-term opioid therapy poses risks and often lacks benefits, necessitating supportive patient-centered tapers.
  • Clinicians and patients face challenges during opioid tapering, including resource limitations and fear of increased pain.

Purpose of the Study:

  • To evaluate the feasibility and acceptability of the Summit web-based app for supporting voluntary opioid tapers.
  • To assess the potential for a full-scale trial of the Summit program through a nine-month randomized pilot feasibility trial.

Main Methods:

  • A randomized pilot feasibility trial (NCT04746833) involving 44 patients over nine months.
  • Participants were randomized to motivational interviewing plus the Summit app or a control pain monitoring app.
  • Feasibility (enrollment, retention, program use) and acceptability (quantitative and qualitative) were primary outcomes.

Main Results:

  • The study achieved a 4.9% enrollment rate, enrolling 44 patients.
  • While Summit website utilization was low, study retention and intervention acceptability were high across both arms.
  • Approximately one-third of participants reduced their opioid dosage, and qualitative feedback indicated positive shifts in pain perception.

Conclusions:

  • The Summit app demonstrates high acceptability and retention, suggesting potential for supporting opioid tapering.
  • Challenges in recruitment and program utilization necessitate modifications to the enrollment strategy for future large-scale trials.
  • Despite low app usage, the pilot provides valuable insights into patient support during opioid dose reduction.