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Related Concept Videos

Uterine Tubes01:16

Uterine Tubes

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The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...
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General Anesthesia: Overview01:24

General Anesthesia: Overview

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Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
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Stages of General Anesthesia01:22

Stages of General Anesthesia

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Various sedation levels offer significant advantages in facilitating procedural interventions for patients undergoing medical or invasive surgical procedures. These levels span from anxiolysis to general anesthesia, providing a spectrum of sedative effects to cater to specific patient needs. Anxiolysis reduces anxiety and is achieved through minimal sedation, enabling patients to remain awake and responsive while feeling more at ease during the procedure. This level can benefit minor...
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Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

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Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
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Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

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Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
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Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

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Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
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Related Experiment Video

Updated: Feb 12, 2026

Mouse Model of Surgically-induced Endometriosis by Auto-transplantation of Uterine Tissue
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Mouse Model of Surgically-induced Endometriosis by Auto-transplantation of Uterine Tissue

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Anesthesia for uterine transplantation.

Ja Eun Lee1, Gaab Soo Kim1

  • 1Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Anesthesia and Pain Medicine
|February 10, 2026
PubMed
Summary

Uterine transplantation (UTx) offers a new path to childbirth for women with uterine infertility. Anesthesiologists are crucial for patient stability during UTx, pregnancy, and delivery, improving fertility restoration success.

Keywords:
Absolute uterine factor infertilityAnesthesia, gynecologicalAnesthesia, transplantationEnhanced recovery after gynecologic surgeryInfertility, femaleOrgan transplantationUterine transplantation

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Area of Science:

  • Reproductive medicine and transplant surgery
  • Anesthesiology and critical care
  • Women's health and fertility restoration

Background:

  • Uterine transplantation (UTx) is a complex procedure for absolute uterine factor infertility.
  • The first live birth via UTx occurred in 2014, spurring rapid advancements.
  • UTx requires multidisciplinary collaboration, including anesthesiology.

Purpose of the Study:

  • To review the history, current status, and future of UTx.
  • To emphasize the critical role of anesthetic management in UTx.
  • To discuss anesthetic considerations for pregnancy and delivery post-UTx.

Main Methods:

  • Review of historical background and clinical experience in UTx.
  • Analysis of anesthetic management strategies for UTx procedures.
  • Examination of anesthetic considerations for pregnancy and cesarean delivery after UTx.

Main Results:

  • Anesthesiologists are vital for physiological stability throughout UTx.
  • Preoperative assessment and intraoperative management are key anesthetic aspects.
  • Anesthetic protocols must evolve with clinical experience and research.

Conclusions:

  • Comprehensive perioperative anesthetic care significantly contributes to UTx success.
  • Anesthesiology is essential for enabling childbirth in women with uterine infertility.
  • Adapting anesthetic protocols is necessary as UTx programs expand.