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Updated: Feb 12, 2026

Orthotopic Liver Transplantation in Rats
Published on: July 1, 2012
A Case Report of Posterior Reversible Encephalopathy Syndrome With Intracranial Hemorrhage After Split-Liver
Jiancheng Wu1, Jiwei Qin2, Xiaodong Yuan2
1Graduate School of Bengbu Medical University, Bengbu, Anhui, China; Department of Liver Transplantation, Organ Transplant Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Abstract:
Transplantation is an efficient way for treating end-stage liver disease, but postoperative problems are extremely common, notably neurological issues, which occur more frequently than in other solid organ transplants (15%-30%). These neurological problems emerge as disturbances in awareness, seizures, central nervous system infections, central pontine myelinolysis, and posterior reversible encephalopathy syndrome (PRES), among others, severely compromising the survival and prognosis of transplant recipients. PRES is relatively rare among central nervous system complications following liver transplantation. Due to the lack of specific clinical manifestations and the variability of imaging results, it often results in a poor prognosis when severe intracranial hemorrhage occurs. This article reports a case of a patient who developed PRES with cerebral bleeding 3 months after liver transplantation, assessing the peculiarities of the case and consolidating experiences to provide a reference for early clinical diagnosis and treatment.
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