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Updated: Feb 12, 2026

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Wounds to Wisdom: Exploring Risk Factors and Outcomes for Surgically Managed Postcesarean Wound Infections.

Janice Wong1,2, Emma E H Peek3, Ysaac Zegeye3

  • 1Department of Obstetrics & Gynecology, Duke University Medical Center, Durham, North Carolina, United States.

AJP Reports
|February 11, 2026
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Summary

Postcesarean surgical site infections (SSIs) requiring surgery lead to increased morbidity and longer hospital stays. Risk factors include higher BMI, hypertensive disorders, and general anesthesia, necessitating closer monitoring for wound infections.

Keywords:
cesarean sectionpostcesarean wound infectionsurgical interventionwound infection

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Area of Science:

  • Obstetrics and Gynecology
  • Infectious Disease Management
  • Surgical Site Infection Research

Background:

  • Postcesarean surgical site infections (SSIs) are a significant cause of maternal morbidity and increased healthcare costs.
  • Current understanding and management strategies for post-SSI interventions remain limited, impacting patient outcomes.

Purpose of the Study:

  • To investigate the rates and risk factors associated with surgical intervention for postcesarean SSIs.
  • To compare outcomes between patients requiring surgical versus conservative management for SSIs.

Main Methods:

  • Retrospective cohort study of 533 patients delivering via cesarean between June 2013 and July 2022.
  • Analysis of factors associated with surgical intervention and comparison of morbidity and hospitalization outcomes.

Main Results:

  • 12.9% of patients (69/533) required surgical management for SSIs.
  • Surgical intervention was associated with higher BMI, hypertensive disorders of pregnancy, general anesthesia, blood transfusion, and penicillin allergy.
  • Patients undergoing surgical intervention experienced higher rates of sepsis, acute kidney injury, fascial dehiscence, and prolonged hospitalizations.

Conclusions:

  • Specific patient factors (e.g., high BMI, hypertensive disorders, general anesthesia) may indicate a need for heightened surveillance for wound infections.
  • Surgical management of postpartum wound infections is linked to increased morbidity and more complex, extended hospitalizations.