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Tween 80/diatrizoate enemas in bowel obstruction
AJR. American Journal of Roentgenology
|April 1, 1978
Summary
Tween 80, a component in Gastrografin enemas, is key for treating meconium ileus by acting as a stool emulsifier. This surface-active substance, at 1%-2% concentration with sodium diatrizoate, effectively relieves intestinal obstruction in infants and children.
Area of Science:
- Pediatric Gastroenterology
- Pharmacology
Background:
- Meconium ileus is a common neonatal surgical emergency.
- Gastrografin enema is a standard treatment, with hypertonicity previously thought to be the primary mechanism.
- The role of other components in Gastrografin has not been fully elucidated.