Prognostic value of left atrial parameters derived from magnetic resonance in dilated cardiomyopathy: a systematic

Qimin Fang1, Yipei Song1, Mengyao Hu1

  • 1Department of Radiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.

Insights

Left atrial strain parameters, including reservoir, conduit, and booster strain, show high predictive value for adverse cardiovascular events in dilated cardiomyopathy (DCM) patients. Left atrial volume parameters have lower predictive value.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Prognostics

Background:

  • Prognostic value of left atrial (LA) parameters in dilated cardiomyopathy (DCM) is debated.
  • Cardiac magnetic resonance (CMR) derived LA structural and functional parameters require further investigation for their prognostic utility in DCM.

Purpose of the Study:

  • To assess the prognostic value of LA structural and functional parameters obtained via CMR in DCM patients.
  • To determine the predictive capability of LA parameters for adverse cardiovascular events in DCM.

Main Methods:

  • Systematic literature search of PubMed, Web of Science, Medline, Embase, and Cochrane Library up to December 12, 2024.
  • Meta-analysis of 13 studies (4,326 patients) evaluating LA parameters and adverse cardiovascular events.
  • Risk of bias assessed using the Quality In Prognosis Studies (QUIPS) tool.

Main Results:

  • Left atrial maximum volume index (LAVImax), minimum volume index (LAVImin), and LA strain parameters predict adverse cardiovascular events in DCM.
  • LA strain parameters, including reservoir strain (LARS), conduit strain (LACS), and booster strain (LABS), demonstrated significant predictive potential.
  • Sensitivity analyses confirmed the stability of LAVImax, LARS, LACS, and LABS; no significant publication bias was detected.

Conclusions:

  • LA strain parameters exhibit high predictive value for adverse cardiovascular events in DCM.
  • LA volume parameters demonstrate relatively lower predictive value compared to strain parameters in DCM prognosis.
Abstract

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