Related Experiment Video
Updated: Feb 12, 2026
![Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F62460.jpg&w=3840&q=50)
Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging
Published on: July 1, 2021
The Role of 68Ga-Pentixafor and 18F-Fluorodeoxyglucose (18F-FDG) PET/CT in a Case of Multiple Myeloma
Abhishek Kumar1, Tamojit Chaudhuri2, Manisha Pradhan3
1Nuclear Medicine, Tata Main Hospital, Jamshedpur, IND.
Abstract:
Multiple myeloma (MM) is a type of blood cancer affecting plasma cells in the bone marrow. The diagnosis of MM involves blood and urine tests to demonstrate monoclonal proteins. Imaging modalities such as MRI combined with positron emission tomography (PET) are used for the detection and staging of MM. 18F-fluorodeoxyglucose (18F-FDG) has been used extensively for the staging of multiple myeloma. Another PET imaging modality targeting C-X-C chemokine receptor type 4 (CXCR4) has been recently evaluated for the staging of MM. CXCR4 is a protein receptor expressed on plasma cells, and the radiolabelled Pentixafor radiotracer targets these receptors and is therefore used in PET imaging. In this case report, we compare FDG and CXCR4 PET radiotracers for staging MM.
Insights
This case report compares two positron emission tomography (PET) radiotracers for staging multiple myeloma (MM). 18F-fluorodeoxyglucose (FDG) and C-X-C chemokine receptor type 4 (CXCR4) targeting Pentixafor show potential for MM detection and staging.
Area of Science:
- Oncology
- Nuclear Medicine
- Radiochemistry
Background:
- Multiple myeloma (MM) is a plasma cell malignancy originating in the bone marrow.
- Diagnosis and staging of MM typically involve blood/urine tests and imaging.
- Positron emission tomography (PET) is a key imaging modality for MM staging.
More Related Videos
10:02Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT
Published on: May 2, 2012
10:53Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
Published on: November 23, 2012
Related Concept Videos
Multiple Allele Traits
Radiological Investigation I: X-ray and CT
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Role of Septins
Cellular Functions of Septins
Recent studies have revealed the multifaceted roles of septins in various cellular processes such as cytokinesis, ciliogenesis, and neurogenesis. Septins act as scaffolds and...
The Role of Culture
Multiple Regression
Farmers can use multiple regression to determine the crop yield based on more than one factor, such as water availability, fertilizer, soil properties, etc. Here, the crop yield is the response or dependent variable as it depends on the other independent variables. The analysis requires the construction of a scatter plot...