Perioperative Care of an Eleven-Year-Old Child With Osteogenesis Imperfecta Type II During Posterior Spinal Fusion

Alaa Soliman1, Marwan Hillis1, Allen Kadado2

  • 1Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.

Journal of Medical Cases
|February 11, 2026
PubMed

Insights

Osteogenesis imperfecta (OI) is a rare genetic disorder causing bone fragility and multi-system issues. Anesthetic management for OI patients requires careful consideration of airway, positioning, respiratory, and coagulation risks during surgery.

Area of Science:

  • Medical Genetics
  • Anesthesiology
  • Orthopedic Surgery

Background:

  • Osteogenesis imperfecta (OI) is an autosomal dominant inherited connective tissue disorder.
  • OI presents with bone fragility, skeletal deformities, and potential cardiovascular, respiratory, and hematologic system involvement.
  • Perioperative management of OI patients is complex due to risks like difficult airways, fracture, restrictive lung disease, and coagulation issues.

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