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Updated: Feb 12, 2026

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Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
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Endoscopic Combined Aortic and Mitral Valve Surgery: Feasibility and Mid-term Outcomes
Giovanni Domenico Cresce1, Daniele Zoni1, Valentina Grazioli1
1Division of Cardiac Surgery, S. Bortolo Hospital, Vicenza 36100, Italy.
Summary
Endoscopic minimally invasive surgery is feasible for combined aortic and mitral valve procedures. This approach shows promising mid-term survival rates, supporting its wider clinical adoption.
Area of Science:
- Cardiovascular Surgery
- Minimally Invasive Techniques
- Thoracoscopic Procedures
Background:
- Endoscopic surgery offers advancements in minimally invasive cardiac procedures.
- Evidence for endoscopic application in combined aortic and mitral valve surgery is limited.
Purpose of the Study:
- To evaluate the feasibility and mid-term outcomes of endoscopic concomitant aortic and mitral valve surgery.
- To assess the safety and efficacy of this minimally invasive approach.
Main Methods:
- Retrospective analysis of 111 patients undergoing endoscopic combined valve surgery (Jan 2016-Jul 2025).
- Procedures performed via right mini-thoracotomy using a thoracoscope with peripheral cardiopulmonary bypass.
- Primary endpoint: in-hospital mortality; Secondary endpoints: postoperative complications and mid-term survival.
Main Results:
- In-hospital mortality was 3.6%, with low rates of stroke (3.6%) and bleeding (8.1%).
- Median follow-up of 46 months showed an overall survival of 87%.
- Reduced eGFR, coronary artery disease, chronic lung disease, and peripheral arteriopathy predicted adverse early outcomes.
Conclusions:
- Endoscopic technique is a viable option for combined aortic and mitral valve surgery.
- The procedure demonstrates favorable mid-term results, supporting its increased use.
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