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Navigating migraine care during pregnancy and lactation
Chelsea K Stone1, Meesha Trivedi2, Soma Sahai-Srivastava1
1Department of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, California.
Current Opinion in Obstetrics & Gynecology
|February 11, 2026
Summary
Migraine management during pregnancy and lactation needs careful planning and safe therapies. Evidence-based strategies ensure maternal health and minimize risks to the baby.
Area of Science:
- Neurology
- Obstetrics
- Pharmacology
Background:
- Migraine management during pregnancy, postpartum, and lactation presents unique challenges.
- Traditional approaches often involve medication avoidance, potentially compromising maternal well-being.
- Recent evidence and guidelines necessitate a more nuanced, evidence-based approach.
Purpose of the Study:
- To review current evidence on migraine management during pregnancy and lactation.
- To provide guideline-based recommendations for acute and preventive migraine treatment.
- To address the safety of migraine-specific therapies during lactation and preconception medication discontinuation.
Main Methods:
- Comprehensive literature review of recent evidence.
- Analysis of guidelines from the American College of Obstetricians and Gynecologists.
- Development of a collaborative, individualized care framework.
Main Results:
- Migraine management requires individualized decision-making, integrating pharmacologic and procedural strategies.
- A collaborative framework balances maternal function preservation with fetal and neonatal risk minimization.
- Low-exposure procedural interventions can reduce migraine disability.
Conclusions:
- Effective migraine care during pregnancy is achievable and essential.
- Structured preconception planning and safe therapy selection are crucial.
- Coordinated neurologic-obstetric care supports maternal health and improves outcomes.
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