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Acute intermittent hemodialysis management: a single center experience
Yasemin Kıraç1, Ayşegül Alpcan2, Yaşar Kandur3
1Division of Nephrology, School of Medicine, Kırıkkale University, Turkey.
Renal Failure
|February 11, 2026
Summary
This study on acute kidney injury (AKI) patients undergoing intermittent hemodialysis (IHD) found that certain biochemical markers predict mortality. Early management of these imbalances may improve outcomes for AKI patients.
Area of Science:
- Nephrology
- Internal Medicine
- Critical Care Medicine
Background:
- Acute kidney injury (AKI) is a common clinical syndrome.
- Intermittent hemodialysis (IHD) is a primary treatment modality for severe AKI.
- Identifying prognostic factors is crucial for managing AKI patients.
Purpose of the Study:
- To evaluate prognostic factors influencing outcomes in patients with AKI treated with IHD.
- To identify predictors of mortality and other adverse outcomes in this patient cohort.
Main Methods:
- Retrospective review of medical records for 193 patients treated with IHD between 2014 and 2024.
- Categorization of patients into outcome groups: recovered, deceased, chronic kidney disease without dialysis (CKD-ND), or chronic kidney disease with dialysis (CKD-D).
- Statistical analysis including multivariate logistic regression to identify independent predictors of mortality.
Main Results:
- The primary indications for dialysis were hypervolemia (64.8%) and uremia (24.9%).
- Overall mortality was high at 50.8%, with 23.8% recovering, 21.2% developing CKD, and 4.1% becoming dialysis-dependent.
- Lower serum creatinine and calcium, and higher serum sodium, urea, and C-reactive protein (CRP) were independent predictors of mortality.
Conclusions:
- Biochemical and inflammatory markers, including creatinine, calcium, sodium, urea, and CRP, are significant prognostic indicators in AKI patients undergoing IHD.
- Early recognition and management of electrolyte and inflammatory derangements may enhance patient survival and recovery.
- Further research into targeted interventions based on these markers is warranted.
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