Reuse and recycle: is autogenous tooth graft effective for alveolar ridge preservation?

Mahardawi B, Jiaranuchart S, Phrueksotsai C, Panya S, Arunjaroensuk S, Pimkhaokham A. Using autogenous tooth graft for alveolar ridge preservation: A systematic review and meta-analysis. J Prosthet Dent. 2025 Apr 28:S0022-3913(25)00299-9.  https://doi.org/10.1016/j.prosdent.2025.04.002 .

A systematic review with meta-analysis was conducted to determine if autogenous tooth graft (ATG) was effective at maintaining alveolar ridge dimensions and stimulating bone formation in patient's undergoing exodontia, compared with spontaneous healing or other bone grafting materials. PRISMA guidelines were adhered to, and PICOS were used to develop the search question.

Three databases and non-peer-reviewed literature were reviewed independently by two authors. Inclusion criteria were randomised controlled trials comparing ATG with spontaneous healing or other grafting materials in human models. Studies that mixed bone grafting materials were excluded.

A meta-analysis assessed clinical significance with a 95% confidence interval, using the standardised mean difference to analyse alveolar ridge changes, and mean difference to assess bone regeneration. The random-effect model was applied to all analyses, and the GRADE system was used to determine the level of effect on ridge dimensions.

After screening, fourteen studies were included in the meta-analysis. ATG was found to significantly reduce horizontal ridge resorption compared with ungrafted sockets, but did not perform superiorly compared with other grafting materials. There was a higher percentage of new bone formation at ATG sites, and no evidence that ATG compromised implant placement.

ATG is a valid alternative to other grafting materials for alveolar ridge preservation and may offer a histological advantage of stimulating more bone formation. Further clinical studies with increased sample size, longer follow-up, and standardised protocols are required to confirm clinical outcomes.