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Periodontitis Prediction Model Using Linked Electronic Health and Dental Records.

J S Patel1, M Tellez1, R Katiyar1

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|February 11, 2026
PubMed
Summary
This summary is machine-generated.

Integrating medical and dental records improves periodontal disease prediction. Dental factors remain key, but systemic conditions offer valuable insights for early intervention and personalized care.

Keywords:
Oral and systemic health connectionartificial intelligencedeep learning/machine learningdental informatics/bioinformaticsperiodontal diseaserisk assessment

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Area of Science:

  • Oral Health Research
  • Medical Informatics
  • Artificial Intelligence in Healthcare

Background:

  • Periodontal disease (PD) is linked to systemic health, yet predictive models often exclude medical data.
  • Existing models focusing solely on dental records limit comprehensive risk assessment.

Purpose of the Study:

  • To enhance periodontal disease (PD) risk prediction by integrating electronic dental records (EDRs) with electronic health records (EHRs) using machine learning (ML).

Main Methods:

  • Utilized EDR and EHR data from adult patients, linking dental and medical information.
  • Developed automated feature reduction techniques for extensive EHR data preprocessing.
  • Trained and evaluated ML models (Gaussian Naive Bayes, Random Forest, LightGBM, XGBoost) using cross-validation.

Main Results:

  • The best model, using chi-square selected features, achieved 85% specificity, 67% sensitivity, and 84% AUC.
  • Dental factors like oral hygiene and smoking status were dominant predictors.
  • Systemic conditions (cardiovascular, endocrine, renal) meaningfully contributed to PD risk prediction.

Conclusions:

  • Strong associations between systemic health and oral health were observed, despite dental factors being primary predictors.
  • Integrating medical and dental records can guide clinicians in identifying high-risk patients for earlier intervention.
  • AI-driven models show potential for personalized care and improved interdisciplinary health management.