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Characterization of the Sense of Agency over the Actions of Neural-machine Interface-operated Prostheses
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Translating 2D Nanomaterials into Neurotherapeutics: From Biomarker Sensing to Bioelectronic Interfaces
Uday Kumar Singh1, Bishal Kumar Nahak1, Jaba Roy Chowdhury1
1Department of Biomedical Engineering, National Taiwan University, Taipei, Taiwan.
Advanced Healthcare Materials
|February 12, 2026
Summary
Two-dimensional (2D) nanomaterials show promise for treating neurological disorders by improving nerve regeneration and neural circuit repair. These advanced materials offer new hope for effective, scalable, and personalized therapies.
Area of Science:
- Neuroscience
- Materials Science
- Biotechnology
Background:
- The mammalian nervous system's complexity presents significant challenges for treating neurological and psychiatric disorders.
- Current therapeutic strategies face limitations like low neuronal survival, poor integration, and immune rejection.
Purpose of the Study:
- To systematically review the properties and applications of 2D nanomaterials in neuroregeneration.
- To explore the potential of 2D nanomaterials for modulating neural and immune responses.
Main Methods:
- Review of physicochemical and biological properties of 2D nanomaterials.
- Analysis of fabrication methods and interaction mechanisms with neural and immune systems.
- Examination of integration with bioelectronic interfaces and neuroscience tools.
Main Results:
- 2D nanomaterials demonstrate potential in modulating immune responses, promoting axonal regeneration, and supporting remyelination.
- Hybrid platforms integrating 2D nanomaterials offer precise monitoring and modulation of neural activity.
Conclusions:
- 2D nanomaterials represent a promising avenue for next-generation neuroregenerative therapies.
- Further development is needed for effective, scalable, and personalized interventions for neurological disorders.
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