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Updated: Feb 13, 2026
18:48
Murine Renal Transplantation Procedure
Published on: July 10, 2009
30.7K
Correlation Between Symptom Clusters and Self-Management in Renal Transplant Recipients: Multicenter Cross-Sectional
Ying Zhang1, Hongqin Li2, Junling Wei3
1The First Affiliated Hospital of Dalian Medical University, Liaoning, China.
Clinical Nursing Research
|February 12, 2026
Summary
Renal transplant recipients experience symptom clusters that negatively impact self-management. The activity endurance cluster is a key factor, requiring clinical attention to improve patient self-care post-transplant.
Area of Science:
- Nephrology
- Psychology
- Nursing
Background:
- Self-management is crucial for renal transplant recipients (RTRs).
- Symptom clusters, unlike single symptoms, are understudied in RTRs.
- Understanding symptom clusters can optimize RTR self-management.
Purpose of the Study:
- To identify symptom clusters in RTRs.
- To examine the relationship between these symptom clusters and self-management.
Main Methods:
- Cross-sectional survey of 381 RTRs from two tertiary hospitals.
- Exploratory factor analysis for symptom cluster identification.
- Multiple regression analysis to assess the correlation between symptom clusters and self-management.
Main Results:
- Four symptom clusters were identified: activity endurance, emotion, neuro-gastrointestinal, and hormone.
- Symptom clusters showed a significant negative correlation with self-management (p < .001).
- The activity endurance cluster was a significant influencing factor on self-management (β = -.209, p < .001).
Conclusions:
- Symptom clusters significantly impair self-management in RTRs.
- The activity endurance cluster poses a substantial risk to self-management.
- Clinical interventions should target the activity endurance cluster to enhance self-management in RTRs.
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