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Updated: Feb 13, 2026

Author Spotlight: Development and Evaluation of a Compound Acne Rodent Model Using C. acnes and Oleic Acid
Published on: November 1, 2024
Sociodemographic, clinical, and behavioral determinants of treatment adherence in acne vulgaris: a multicenter study
Arzu Ferhatosmanoğlu1, İbrahim Etem Arıca1, Mualla Polat2
1Department of Dermatology and Venereology, Karadeniz Technical University, Trabzon, Turkey.
Background:
This multicenter study aimed to evaluate treatment adherence and satisfaction among patients with acne vulgaris.
Methods:
A total of 2,349 patients from 18 dermatology centers across Türkiye completed structured questionnaires.
Results:
The participants were predominantly female (79.4%) with a mean age of 21.6 years. Overall, 48% reported consistent adherence to therapy, with significantly lower adherence among males (p < 0.001). The most frequent reasons for nonadherence were forgetfulness (28.7%), dislike of the treatment (26.4%), and reluctance to maintain long-term therapy (21.5%). Treatment adherence was positively associated with higher educational levels (p = 0.006) and greater acne severity (p < 0.001). Logistic regression revealed that systemic oral therapy (OR = 4.37, 95% CI: 3.147-6.086; p < 0.001) and oral isotretinoin (OR = 4.81, 95% CI: 3.379-6.869; p < 0.001) significantly increased adherence compared to topical therapy. Oral treatment was also independently associated with greater satisfaction (OR = 2.33, 95% CI: 1.767-3.095; p < 0.001). Moreover, mild acne severity (OR = 1.67, 95% CI: 1.216-2.297; p = 0.002) and older age (per year; OR = 1.05, 95% CI: 1.020-1.088; p = 0.001) predicted higher satisfaction.
Conclusion:
Systemic therapies-particularly oral isotretinoin-were associated with improved adherence and satisfaction.
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