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Updated: Feb 13, 2026
08:12
Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
Published on: July 15, 2015
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Dual Kidney Transplantation Offers Prolonged Graft Survival
Ekaterina Fedorova1, Sofia Nehring Firmino2, David Foley1
1Division of Transplant Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Clinical Transplantation
|February 12, 2026
Summary
Dual kidney transplantation (DKT) offers better medium-term outcomes than single kidney transplants (SKT) without increasing immediate complications. This approach improves organ utilization and patient access to kidney transplants.
Area of Science:
- Nephrology
- Transplantation Surgery
- Organ Donation
Background:
- Dual kidney transplantation (DKT) is an uncommon procedure utilizing nonstandard kidneys.
- DKT offers a unique approach to organ utilization in kidney transplantation.
Purpose of the Study:
- To compare perioperative and five-year posttransplant outcomes of DKT versus single kidney transplantation (SKT).
- To evaluate the efficacy of DKT in utilizing marginal donor kidneys.
Main Methods:
- Retrospective analysis of adult deceased donor kidney-alone transplant recipients from 2001-2020.
- Comparison of perioperative outcomes (DGF, LOS, rehospitalization, reoperation) and five-year outcomes (AR, DCGF, UCGF, DWFG) between DKT and SKT groups.
Main Results:
- DKT recipients were older and more often male, with higher rates of early steroid withdrawal.
- DKT was not associated with increased perioperative complications (DGF, LOS, reoperation, rehospitalization) compared to SKT.
- DKT demonstrated significantly lower rates of acute rejection, death-censored graft failure, and uncensored graft failure within five years.
Conclusions:
- DKT provides superior medium-term graft survival compared to SKT in selected recipients.
- DKT does not compromise perioperative outcomes and enhances organ utilization.
- DKT increases access to transplantation, particularly for kidneys that might otherwise be discarded.
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