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2D Hybrid Functional Materials for Biological Interfaces
Xiaohui Li1, Haopeng Li2, Changyi Liu1
1School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.
ACS Nano
|February 12, 2026
Summary
This review explores two-dimensional (2D) hybrid functional materials for biological interfaces. These advanced materials show promise in flexible electronics, tissue engineering, and cell stimulation applications.
Area of Science:
- Materials Science
- Biotechnology
- Nanotechnology
Background:
- Two-dimensional (2D) materials possess unique properties driving interdisciplinary research and nano/atomic-scale applications.
- The development of 2D materials has led to hybrid functional materials for studying material-biological tissue interfaces.
- Investigating these interfaces is crucial for advancing biological interface research.
Purpose of the Study:
- To provide an overview of fabricating 2D hybrid functional materials.
- To review the advanced applications of these materials at biological tissue and cellular interfaces.
- To discuss current challenges in their application.
Main Methods:
- Highlighting recent progress in developing 2D hybrid materials with specific functionalities and morphologies.
- Reviewing advanced applications in flexible/implantable electronics, tissue/bone scaffolds, and cell regulation/stimulation.
- Discussing challenges and future directions for 2D hybrid functional materials.
Main Results:
- 2D hybrid functional materials exhibit characteristic functionalities and diverse morphologies.
- These materials have demonstrated advanced applications in various biomedical fields.
- Significant progress has been made in their fabrication and application.
Conclusions:
- 2D hybrid functional materials are effective for devices and biological interfaces.
- They are significant for studying reaction processes and effects at biological interfaces.
- Further research into these materials will advance biological interface applications.
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