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Updated: Feb 13, 2026

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Kauro, a graph-based chatbot for high-fidelity information transmission conversations.

Charles Hadley King1, Rebekah Barrick1, Miguel Almalvez1

  • 1University of California, Irvine, Institute for Clinical and Translational Science.

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Summary

Kauro is an open-source chatbot for biomedical communication, offering reproducible and auditable informed consent conversations. It uses scripted, deterministic paths for safety and trust in sensitive data exchange.

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Area of Science:

  • Biomedical informatics
  • Clinical research technology
  • Artificial intelligence in healthcare

Background:

  • Informed consent is critical but complex, labor-intensive, and inconsistent across sites.
  • Current digital tools for informed consent lack reproducibility and auditability.
  • Generative AI chatbots introduce risks like hallucination and regulatory non-compliance.

Purpose of the Study:

  • To introduce Kauro, an open-source, graph-based chatbot for secure and reliable biomedical communication.
  • To address the limitations of existing platforms in informed consent processes.
  • To enhance reproducibility, auditability, and regulatory oversight in clinical research and care.

Main Methods:

  • Developed Kauro, an open-source chatbot utilizing graph-based structures.
  • Encoded scripted conversations as version-controlled JavaScript Object Notation (JSON) files.
  • Implemented deterministic traversal, comprehensive audit logging, and modular client-server architecture.

Main Results:

  • Kauro ensures deterministic conversation paths, enhancing predictability and safety.
  • The platform provides complete audit logs, facilitating IRB-verifiable oversight.
  • Modular design ensures portability and scalability across different institutions.

Conclusions:

  • Kauro offers a scalable solution for safe, precise, and trustworthy biomedical communication.
  • It reframes the deployment of AI in healthcare by prioritizing reproducibility and auditability.
  • The platform is generalizable to any domain requiring secure and verifiable conversational data.