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Smartphone app-based Integrated Cognitive Control Training for Anxiety Disorders: Study protocol for a Multi-site
This study tests Integrated Cognitive Control Training (ICCT) for anxiety disorders, using a smartphone app to improve cognitive function and reduce symptoms. Findings will assess the feasibility and scalability of this digital intervention for anxiety.
Area of Science:
- Neuroscience
- Clinical Psychology
- Digital Health
Background:
- Anxiety disorders (ADs) are linked to cognitive deficits, impairing clinical and socio-occupational functioning.
- Targeted interventions are crucial for managing cognitive dysfunction in ADs.
Purpose of the Study:
- To evaluate the efficacy of Integrated Cognitive Control Training (ICCT) in adults with ADs through a multi-site randomized controlled trial (RCT).
- To assess ICCT's impact on cognitive functions, anxiety symptoms, and neural circuits of cognitive control.
- To determine the feasibility and scalability of a smartphone-delivered ICCT program for ADs.
Main Methods:
- A multi-site RCT involving 100 adults diagnosed with ADs, randomized to ICCT or Treatment As Usual (TAU).
- ICCT delivered via weekly therapist-guided sessions and a smartphone app (Cogtrain) for homework.
- Multimodal assessments including clinical scales (Hamilton Anxiety Rating Scale), neuropsychological tests, and fMRI at multiple time points.
Main Results:
- Expected to demonstrate enhancement in cognitive functioning and reduction in anxiety symptoms following ICCT.
- Anticipated changes in the neural circuits of cognitive control, as evidenced by fMRI.
- Feasibility and acceptance metrics will be recorded to inform intervention scalability.
Conclusions:
- ICCT shows potential as an effective intervention for improving cognitive and overall functioning in adults with ADs.
- Smartphone-delivered ICCT offers a scalable and cost-effective approach, particularly for resource-constrained settings.
- This study protocol outlines a rigorous evaluation of a novel digital intervention for anxiety disorders.
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