Related Experiment Video
Updated: Feb 13, 2026

Methylated RNA Immunoprecipitation Assay to Study m5C Modification in Arabidopsis
Published on: May 14, 2020
RBM15 in diseases: Molecular mechanisms and clinical opportunities from RNA m6A methylation
Fengze Li1,2, Junzhe Liu1,3,4,5,6, Na Wang7
1Department of Neurosurgery, The 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, China.
None:
RNA m6A methylation is the most common type of RNA modification, and RBM15 regulates various cellular processes by writing m6A methylation on RNA. m6A methylation mediated by RBM15 significantly affects RNA stability and translational efficiency, thereby regulating gene expression. In-depth studies have revealed that RBM15 affects the progression of various diseases by regulating the expression of multiple genes, and its m6A methylation modification process is also considered to be an effective therapeutic target. In this paper, we review the latest research progress on the regulation of m6A methylation modification of RBM15, its molecular regulation in various diseases, such as cancer and metabolic diseases, and the potential therapeutic drugs derived from it, with a view to providing therapeutic strategies for the subsequent research on RBM15 and gene therapy targeting RBM15.
Related Concept Videos
Chronic Kidney Disease II: Clinical Manifestations
Ribosomal RNA Synthesis
Ribosome biogenesis begins with the synthesis of 5S and 45S pre-rRNAs by distinct RNA polymerases. The primary transcripts are extensively processed and modified before they are bound and folded by ribosomal proteins and assembly factors,...
Coronary Artery Disease III: Clinical Manifestations
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Transfer RNA Synthesis
Each of these chemical modifications is carried by a specific enzyme, post-transcription. All of these enzymes have unique base and site-specificity. Methylation, the most common chemical modification, is carried by at least nine different enzymes, with...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

