Feasibility randomized controlled trial of a home-based support program for family caregivers of people with Alzheimer's disease
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Hongli Liu1,2, Yuanli Jiang3,4, Jiajia Chen2
1Department of Critical Care Medicine, Chongqing General Hospital, Chongqing University, Chongqing, China.
Objective:
This study aimed to develop and preliminarily evaluate the feasibility of a home-based care program for family caregivers of individuals with Alzheimer's disease (AD).
Methods:
We developed a home-based intervention for AD caregivers through systematic literature review and two-round Delphi consensus (18 experts; authority coefficients 0.88-0.91). This feasibility randomized controlled trial enrolled 61 primary caregivers and assigned them to either an experimental group (n=31) receiving a structured, evidence-based, 3-month home-care protocol, or a control group (n=30) receiving conventional nursing guidance.
Results:
The Delphi process achieved strong expert consensus. Post-intervention, caregivers in the intervention group demonstrated significant improvements in AD knowledge scores, anxiety reduction, and psychological domain QOL-AD scores compared to baseline (P < 0.05). While total QOL-AD scores increased in the intervention group, between-group differences were not statistically significant.
Conclusion:
The home-based care program proved feasible and effective in enhancing AD caregiver knowledge and mental health outcomes. These promising findings support the need for larger-scale efficacy trials to further validate clinical utility.
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