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Updated: Feb 13, 2026

Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy
Published on: October 4, 2019
Functional and evolutionary characterization of potential auxiliary metabolic genes of the global RNA virome
Yang Zhao1,2,3,4, Zhihao Zhang5,6, Meiling Feng1,2,3,4
1College of Ecology Lanzhou University Lanzhou China.
Abstract:
We generated the first comprehensive view of RNA viral auxiliary metabolic genes (AMGs), expanding the known functional type of AMGs by 75%. RNA viruses encode a remarkably high diversity of AMGs, spanning 25 distinct functional categories. Most of these genes are linked to environmental regulation and genetic information processing, with fewer associated with nutrient cycling. Additionally, RNA viruses carrying AMGs are capable of infecting both eukaryotes and prokaryotes, and may acquire AMGs from organisms beyond their predicted host range.
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