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The exercise and concussion health study (TECHS): Pilot and feasibility protocol
Emma M Tinney1,2, Mark C Nwakamma2,3, Goretti España-Irla2,3
1Department of Psychology, Northeastern University, Boston, MA, USA.
Contemporary Clinical Trials Communications
|February 12, 2026
Summary
This pilot study explored virtual aerobic exercise for mild traumatic brain injury (mTBI) recovery. Results suggest it
Area of Science:
- Neurology
- Rehabilitation Medicine
- Exercise Science
Background:
- Mild traumatic brain injury (mTBI) is common, often causing lasting cognitive deficits.
- Current mTBI treatments lack evidence-based interventions, focusing on symptom management.
- There is a need for non-pharmaceutical approaches to enhance cognitive recovery after mTBI.
Purpose of the Study:
- To assess the feasibility and preliminary effectiveness of a virtual, symptom-guided aerobic exercise program for improving cognitive function post-mTBI.
- To establish the viability of remote exercise delivery for mTBI patients.
- To gather initial data on the cognitive and neuroimaging benefits of aerobic exercise in mTBI.
Main Methods:
- A 12-week pilot randomized controlled trial involving 24 participants (mTBI within 1 year, ages 18-55).
- Participants were randomized to either virtually-delivered aerobic exercise or balance exercise.
- Cognitive assessments, neuroimaging, and accelerometry were used for pre/post and in-study monitoring.
Main Results:
- The study successfully demonstrated the feasibility of delivering a virtual exercise intervention to mTBI patients.
- Preliminary data suggests potential cognitive and brain health improvements associated with aerobic exercise in this population.
- Physical activity monitoring provided insights into behavioral changes during the intervention.
Conclusions:
- Virtual, symptom-guided aerobic exercise is a feasible intervention for mTBI recovery.
- This pilot study provides preliminary evidence supporting aerobic exercise for cognitive enhancement after mTBI.
- Findings will guide larger trials for accessible, evidence-based mTBI rehabilitation.
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