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Adolescent social-media exposure and cortical thinning signals: latest 2025 MRI-epigenome correlations
Syeda Tayyaba Batool1, Umair Ali2, Raghabendra Kumar Mahato3
1Department of Medicine, Azad Jammu and Kashmir Medical College, Muzaffrabad, Pakistan.
Abstract:
Large 2025 adolescent cohorts combining high-resolution MRI with epigenomic profiling now demonstrate that excessive social-media exposure correlates with early cortical thinning signals, neuroinflammatory promoter activation, and impaired attention-executive network maturation. These effects are linked to microglial cytokine priming and activity-dependent chromatin stress rather than structural neurodevelopmental disorders. Emerging data suggest modifiable risk windows through behavioral restriction modeling and inflammation-calming drug-neutral adjuncts without disrupting digital literacy frameworks.
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