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Artificial Intelligence in Cerebrovascular Imaging: A Targeted Review of Aneurysm Detection and Rupture Risk
1Department of Biomedical Engineering, University of Massachusetts Amherst, Amherst, MA, USA.
JMA Journal
|February 12, 2026
Summary
Artificial intelligence (AI) offers advanced tools for detecting cerebral aneurysms and predicting rupture risk, surpassing traditional methods. While promising, AI applications require further clinical validation before widespread adoption for personalized patient care.
Area of Science:
- Neuroimaging
- Vascular Neurology
- Artificial Intelligence in Medicine
Background:
- Cerebral aneurysms pose significant risks, with traditional imaging limited in predicting rupture.
- There is a critical need for advanced, individualized diagnostic strategies to improve patient outcomes.
- Artificial intelligence (AI) presents transformative potential in cerebrovascular imaging and aneurysm management.
Purpose of the Study:
- To review and synthesize the application of AI in cerebrovascular imaging for aneurysm detection and rupture risk prediction.
- To provide an integrated framework for radiomics, machine learning (ML), and deep learning (DL) in aneurysm analysis.
- To highlight emerging AI solutions and address challenges for clinical translation.
Main Methods:
- Narrative review of published studies on AI in cerebrovascular imaging.
- Examination of radiomics for quantitative feature extraction.
- Analysis of ML and deep learning (DL) models for detection and risk prediction.
Main Results:
- Radiomics, ML, and DL offer enhanced capabilities for aneurysm detection and rupture risk assessment.
- AI methods show potential to outperform traditional risk scores like PHASES and ELAPSS.
- Current AI approaches are investigational and require rigorous prospective validation.
Conclusions:
- AI, encompassing radiomics, ML, and DL, holds significant promise for personalized aneurysm care.
- Clinical validation and standardization are essential for the successful integration of AI into practice.
- AI-driven precision medicine can potentially reduce aneurysm rupture rates and improve patient outcomes.
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