Related Experiment Video
Updated: Feb 13, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Preoperative Radar Localisation of Impalpable Breast and Axillary Lesions: Initial Experience in an Australian
Grace Carpenter1, Coralie Simoni1, Lucy Lu2
1Department of Medical Imaging, Western Health, Melbourne, Victoria, Australia.
Introduction:
Image-guided radar localisation (RL) is a wire-free alternative to hookwire localisation (HWL) for preoperative localisation of impalpable breast and axillary lesions, with potential logistical and technical advantages. This study assesses clinical utility, accuracy of placement and surgical oncologic outcome metrics for RL using the SCOUT reflector compared to HWL after introduction in a tertiary Australian breast service.
Methods:
Retrospective comparative cohort analysis of consecutive RL with a contemporaneous historical HWL cohort of similar size (between January 2022 and March 2025) was performed. Key outcome markers included device migration, localisation procedure duration, retrieval issues, surgical margin status and breast malignancy re-excision rates.
Results:
287 patients were included (RL n = 144; HWL n = 143). No significant device migration was seen with RL compared to HWL (0.0% vs. 4.2%; p = 0.04) and retrieval issues were less common (4.2% vs. 9.8%; p = 0.10). Excluding MRI placement, procedure duration was shorter with RL (23 min vs. 28 min; p < 0.01). Negative, close, and positive margins were similar and re-excision rates for breast malignancy comparable (12.5% RL vs 16.8% HWL, p = 0.42).
Conclusion:
RL is a safe, accurate localisation technique, demonstrating significantly fewer migration issues and fewer retrieval issues than HWL, while maintaining equivalent surgical oncologic outcomes. It offers logistical benefits of placement at any time prior to surgery (including time-of-biopsy placement), optimisation of radiology and surgical workflows, and versatility of axillary node and MRI-guided placement and compatibility.
More Related Videos
07:13Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer
Published on: March 26, 2014
09:49Non-enzymatic, Serum-free Tissue Culture of Pre-invasive Breast Lesions for Spontaneous Generation of Mammospheres
Published on: November 8, 2014
Related Concept Videos
Tertiary Healthcare System
Initiation of Translation
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
Initiation of Translation
Nomenclature of Secondary and Tertiary Amines
Transcription Initiation
The promoters and enhancers and their accessory proteins allow tight regulation of...
What is an Experiment?