Related Experiment Video
Updated: Feb 13, 2026

Amplifying and Quantifying HIV-1 RNA in HIV Infected Individuals with Viral Loads Below the Limit of Detection by Standard Clinical Assays
Published on: September 26, 2011
Clinical and HIV Surveillance Data to Determine Care Status for People With HIV in Washington, DC
Lauren O'Connor1, Shannon Hammerlund1, Lisa Mele2
1The Milken Institute School of Public Health, George Washington University, Washington, DC.
Background:
We examined factors related to being out of care (OOC) or reentering care after clinic transfer among people with HIV in Washington, DC using clinical and linked surveillance data from the DC Department of Health (DC Health).
Methods:
Using DC Cohort HIV care encounters and laboratory results, linked surveillance data, and chart review, we determined if participants were (1) engaged in care; (2) OOC; (3) died; (4) withdrew; (5) clinic-reported transfer; (6) surveillance-based transfer (using DC Health data); and (7) undetermined. Of the clinic-reported transfers, we used surveillance data to determine whether participants reentered care after transfer. We evaluated associations between participant characteristics, being OOC, and reentering care using logistic regression.
Results:
We evaluated 12,563 DC Cohort participants, 6557 (52.5%) were engaged in care, 748 (6.0%) OOC, 1893 (15.0%) clinic-reported transfers, 1692 (13.5%) surveillance-based transfers, 1418 (11.0%) died, 41 (0.3%) withdrew, and 214 (1.7%) were undetermined. Of clinic-reported transfers, 832 (44.0%) reentered care, with 80.9% achieving viral suppression (<200 copies/mL). In the adjusted analysis, females, older age, non-Hispanic Black race, longer time since HIV diagnosis, CD4 ≥ 500 cells/µL, former or never smoking, and public insurance were associated with being engaged in care. Similarly, non-Hispanic Black race, non-Hispanic White race, nonviral suppression, Ryan White clinic, former alcohol abuse, and temporary/unstable housing were associated with reentering care among the clinic-reported transfers, after adjusting for covariates.
Conclusions:
Individual, clinical, and structural factors were associated with being OOC or care reentry. Targeted interventions addressing these factors may improve sustained HIV care and reduce transmission.
Related Concept Videos
DC Generator
Statistical Software for Data Analysis and Clinical Trials
DC Battery
Principles of Disease Surveillance
One-Compartment Open Model: Urinary Excretion Data and Determination of k
Immune Surveillance by NK Cells and Phagocytes
Natural Killer Cells: The Fast Responders
NK cells are large granular lymphocytes found in the blood and lymphatic system. These...

