Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Growth Models with Integration: Problem Solving01:27

Growth Models with Integration: Problem Solving

64
In population modeling, integration provides a systematic way to determine accumulated quantities from known rates of change. One such application arises in ecology, where the total weight of a fish population in a body of water is referred to as its biomass. When the rate of growth of this biomass is known as a function of time, calculus can be used to determine the total biomass at a future date.Growth Rate and Biomass FunctionLet the growth rate of the fish population be represented by a...
64
Integration by Parts: Indefinite Integrals01:26

Integration by Parts: Indefinite Integrals

242
Integration by parts is a fundamental technique in calculus for evaluating integrals involving the product of two functions. It is particularly useful when direct integration is not feasible. The method is based on the product rule for differentiation, which states that the derivative of a product equals the derivative of the first function times the second, plus the first function times the derivative of the second. By integrating this identity and rearranging terms, the integration by parts...
242
Integration by Parts: Definite Integrals01:23

Integration by Parts: Definite Integrals

93
Definite integrals involving the product of two functions over a fixed interval can be evaluated using integration by parts. This method rewrites the integral as the difference of a product evaluated at the endpoints and a remaining definite integral that is often simpler to compute.A representative example is the definite integral of the inverse tangent function. Since there is no direct integration formula for arctan ⁡x, the integrand is rewritten as a product of arctan⁡ x and the...
93
In Vitro Drug Release Testing: Overview, Development and Validation01:10

In Vitro Drug Release Testing: Overview, Development and Validation

368
In vitro dissolution and drug release tests assess how quickly and how much of a drug is released from its dosage form into an aqueous medium under standardized laboratory conditions. These tests are essential tools in pharmaceutical development and quality assurance, offering insight into the drug's performance before clinical use.During formulation development, dissolution testing identifies incomplete or inconsistent drug release issues. It also supports decisions on selecting the optimal...
368
Embryonic Stem Cells00:58

Embryonic Stem Cells

32.7K
Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
32.7K
Sustainable Development01:43

Sustainable Development

15.2K
As the human population continues to grow and use resources, we must be mindful of our planet’s natural limits. Sustainable development provides a pathway to maintain and improve human life now while also ensuring that future generations will have the resources that they need. The long-term success of sustainability efforts rests on understanding the interplay between human actions and ecological systems.
15.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Self-supported catalysts.

Chemical reviews·2008
Same author

[The local control of radiotherapy following Ivor-Lewis esophagectomy in the patients with stage II A middle-third thoracic esophageal cancer].

Zhonghua wai ke za zhi [Chinese journal of surgery]·2008
Same author

Magnetic loading of carbon nanotube/nano-Fe(3)O(4) composite for electrochemical sensing.

Talanta·2008
Same author

Carbon nanotube/polystyrene composite electrode for microchip electrophoretic determination of rutin and quercetin in Flos Sophorae Immaturus.

Talanta·2008
Same author

[Observation on efficacy of large volume whole lung lavage in treatment of pneumoconiosis].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases·2008
Same author

[Application of large volume whole lung lavage in pneumoconiosis].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases·2008

Related Experiment Video

Updated: Feb 14, 2026

Reconstruct Human Retinoblastoma In Vitro
06:52

Reconstruct Human Retinoblastoma In Vitro

Published on: October 11, 2022

1.8K

Reconstructing Early Human Embryonic Development: From in vitro Models to Multimodal Integration.

Gang Chen1,2,3, Zhiyuan Guo1,2,3, Hongmei Wang4,5,6

  • 1State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.

Cells, Tissues, Organs
|February 12, 2026
PubMed
Summary

Studying early human embryonic development is crucial for understanding pregnancy health. Advanced in vitro culture and non-human primate models provide new insights into embryogenesis, aiding research into birth defects.

Keywords:
Human embryonic developmentIn vitro culture of embryosSingle-cell RNA sequencingSpatiotranscriptomics

More Related Videos

Eye Irritation Test EIT for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial RhCE Tissue Model
10:13

Eye Irritation Test EIT for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial RhCE Tissue Model

Published on: August 23, 2015

40.2K
An In Vitro Skin Irritation Test SIT using the EpiDerm Reconstructed Human Epidermal RHE Model
21:16

An In Vitro Skin Irritation Test SIT using the EpiDerm Reconstructed Human Epidermal RHE Model

Published on: July 13, 2009

69.1K

Related Experiment Videos

Last Updated: Feb 14, 2026

Reconstruct Human Retinoblastoma In Vitro
06:52

Reconstruct Human Retinoblastoma In Vitro

Published on: October 11, 2022

1.8K
Eye Irritation Test EIT for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial RhCE Tissue Model
10:13

Eye Irritation Test EIT for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial RhCE Tissue Model

Published on: August 23, 2015

40.2K
An In Vitro Skin Irritation Test SIT using the EpiDerm Reconstructed Human Epidermal RHE Model
21:16

An In Vitro Skin Irritation Test SIT using the EpiDerm Reconstructed Human Epidermal RHE Model

Published on: July 13, 2009

69.1K

Area of Science:

  • Developmental Biology
  • Reproductive Science
  • Genomics

Background:

  • Early human embryonic development influences lifelong health.
  • Aberrations in embryogenesis are linked to adverse pregnancy outcomes.
  • Direct observation of human embryos is limited by ethical and technical challenges.

Purpose of the Study:

  • To review advancements in early primate embryo development research.
  • To highlight the role of in vitro culture (IVC) systems.
  • To discuss integrating experimental models with spatiotranscriptomic atlases.

Main Methods:

  • Utilizing in vitro culture (IVC) systems for human embryo development.
  • Employing non-human primate (NHP) models for extended embryo culture.
  • Analyzing rare early-stage primate embryos from clinical procedures.
  • Integrating experimental models with spatiotranscriptomic atlases.

Main Results:

  • IVC systems support human embryo development to the primitive streak stage.
  • NHP models enable study of development up to neurulation and early organogenesis.
  • Complementary insights are gained from rare clinical embryos.
  • Integration of models provides a comprehensive framework for early development.

Conclusions:

  • Primate IVC systems offer dynamic observation and perturbation platforms.
  • In vivo embryos serve as physiologically accurate references.
  • Combining IVC and in vivo approaches reconstructs early human development.
  • This framework aids in deciphering birth defect causes and drug screening.