Related Experiment Video
Updated: Feb 14, 2026
10:10
Reverse Total Shoulder Arthroplasty
Published on: July 5, 2011
44.0K
Bullous Pemphigoid Following Total Knee Arthroplasty: A Case Report
Aleksandra Małolepsza1, Filip Brzeszczyński2, Oktawiusz Bończak2
1Department of Dermatology, Medical University of Lodz, Lodz, Poland.
JBJS Case Connector
|February 12, 2026
Summary
Surgery can trigger bullous pemphigoid (BP), a blistering skin condition. Early diagnosis and treatment with methotrexate and clobetasol are crucial for recovery.
Area of Science:
- Dermatology
- Immunology
Background:
- Post-surgical complications can manifest in various ways.
- Bullous pemphigoid (BP) is an autoimmune blistering disease.
Purpose of the Study:
- To report a case of bullous pemphigoid triggered by total knee arthroplasty.
- To emphasize the importance of recognizing surgery-induced BP for prompt management.
Main Methods:
- A case study of a 72-year-old woman following knee arthroplasty.
- Diagnostic methods included direct and indirect immunofluorescence, and ELISA.
- Treatment involved oral methotrexate and topical clobetasol.
Main Results:
- The patient developed tense blisters, erosions, and eczematous lesions post-surgery.
- Diagnosis of bullous pemphigoid was confirmed via immunofluorescence and ELISA.
- Treatment led to resolution of blistering within 4 weeks.
Conclusions:
- Surgery can be an inciting event for bullous pemphigoid.
- Timely diagnosis and treatment are essential for favorable outcomes in surgery-induced BP.
Keywords:
BPDIFIIFIgG depositionMTXTKAamplitude SCORE systemautoimmune blistering disorderbullous pemphigoidcemented bicompartmentalcomplement C3 depositioncorticosteroid contraindicationcutaneous blisterdermatologic complicationdifferential diagnosisdirect immunofluorescenceelderlyelderly frailtyerosionsimmunosuppressive therapyindirect immunofluorescenceknee replacementmethotrexatemisdiagnosismultidisciplinary managementoral mucosal involvementorthopedic awarenessosteoarthritispostoperative complicationpruritussteroid-sparing therapysubepidermal blistering diseasetense blistertopical clobetasoltotal knee arthroplasty
Related Concept Videos
01:23Knee Joint
3.3K
The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
3.3K
01:24Data Reporting and Recording
5.5K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.5K
01:25Types of Reports I: Hands-off Report
1.6K
A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
Following are the key components and categories of hand-off reports:
Purpose and Process:
1.6K
01:21Types of Reports II: Incident or Occurrence Report
1.3K
An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
1.3K
01:12Total Voids in Concrete
502
Total voids in concrete encompass gel water volume, capillary pores, and entrapped air. Gel water (retained within the cement hydration products) and physically entrapped or adsorbed water are significant for the hydration process. For complete hydration, it's estimated that the space needed for the products of a cubic centimeter of cement doubles. Capillary pores constitute the unoccupied space within the hydrated cement paste, with their size largely influenced by the water-to-cement...
502
01:26Types of Reports III: Telephone and Verbal Reports
1.0K
Telephone and Verbal Reports in healthcare settings are two communication methods for conveying therapeutic instructions from healthcare providers to nurses or other healthcare staff.
Here's an overview of each type:
Telephone Orders
Here's an overview of each type:
Telephone Orders
1.0K