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Related Concept Videos

Histone Modification02:32

Histone Modification

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The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
Acetylation
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Tracheostomy Suctioning II: Procedure01:23

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Suctioning the Nasopharyngeal Airway01:29

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Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
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Suctioning the Oropharyngeal Airway01:25

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In preparing for oropharyngeal airway suctioning, a nurse must gather all necessary equipment, including a suction unit with tubing, a prepackaged suction kit, sterile gloves, water or saline for irrigation, a water-soluble lubricant, and additional personal protective equipment (such as a gown, mask, and goggles) to control infections.
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Spreading of Chromatin Modifications02:25

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The histone proteins in the nucleosomes are post-translationally modified (PTM) to increase or decrease access to DNA. The commonly observed PTMs are methylation, acetylation, phosphorylation, and ubiquitination of lysine amino acids in the histone H3 tail region. These histone modifications have specific meaning for the cell. Hence, they are called "histone code". The protein complex involved in histone modification is termed as "reader-writer" complex.
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Closed-suction fat harvest using a drain bottle: A practical modification.

Vasiliki Fesatidou1, Abdulla Ibrahim1, Kavan S Johal2

  • 1Department of Plastic and Reconstructive Surgery, St Thomas' Hospital, London SE1 7EH, United Kingdom.

Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS
|February 12, 2026
PubMed
Summary
This summary is machine-generated.

This study introduces a modified fat harvesting technique for autologous fat grafting. The simple adaptation enhances control and reduces harvest time using standard equipment, offering a cost-effective solution.

Keywords:
Adjustable suctionClosed suctionClosed suction drain systemFat harvestLipofilling

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Area of Science:

  • Plastic Surgery
  • Regenerative Medicine
  • Biomaterials Science

Background:

  • Autologous fat grafting is a common method for tissue augmentation.
  • Current fat harvesting techniques lack a universally superior method.
  • Variations exist, but none have definitively proven better than others.

Purpose of the Study:

  • To present a simple modification to a standard fat harvesting technique.
  • To improve control over suction pressure and reduce procedure time.
  • To offer a cost-effective and versatile fat harvesting solution.

Main Methods:

  • Utilized a standard liposuction cannula connected to a closed-suction drain bottle.
  • Connected the drain bottle to a surgical suction unit for continuous pressure control.
  • Modified the technique to prevent negative pressure loss during cannula removal.

Main Results:

  • Achieved continuous control of suction pressure.
  • Reduced overall fat harvesting time.
  • Demonstrated a cost-effective and operator-controlled method.

Conclusions:

  • The described modification offers a practical improvement for autologous fat harvesting.
  • This technique is versatile, cost-effective, and uses readily available equipment.
  • It provides enhanced control and efficiency in fat grafting procedures.