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Managing Obesity in Heart Failure Patients: Current Evidence and Strategies
Shriya Sharma1, Ganesh Giri2, Aarti Desai1
1Division of Advanced Heart Failure and Transplantation, Mayo Clinic, 4500 San Pablo Road, Jacksonville, Florida.
The American Journal of Cardiology
|February 12, 2026
Summary
Obesity significantly impacts heart failure patients, increasing health risks. Managing obesity through multidisciplinary strategies can improve quality of life and functional status in heart failure.
Area of Science:
- Cardiology
- Metabolic Disorders
- Public Health
Background:
- Obesity, defined as excess adipose tissue, is a major global health concern.
- It is linked to diabetes, cardiovascular disease, hypertension, and inflammation, increasing heart failure risk.
- Obesity prevalence is projected to rise significantly by 2035.
Purpose of the Study:
- To review current evidence on managing obesity in heart failure patients.
- To explore the impact of obesity on heart failure complications.
- To discuss advanced therapy options for eligible heart failure patients with obesity.
Main Methods:
- This is a review article.
- It synthesizes existing research on obesity management in heart failure.
- It examines multidisciplinary treatment strategies and advanced therapies.
Main Results:
- Obesity exacerbates heart failure through cardiovascular events, insulin resistance, and inflammation.
- Multidisciplinary management, including physical therapy, nutrition, pharmacotherapy, and bariatric surgery, can improve patient outcomes.
- Addressing obesity enhances functional status and quality of life for heart failure patients.
Conclusions:
- Effective obesity management is crucial for heart failure patients.
- A multidisciplinary approach is essential for comprehensive care.
- Advanced therapies like heart transplants or LVADs may be considered for select patients with end-stage heart failure and obesity.
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