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Related Concept Videos

Translesion DNA Polymerases02:10

Translesion DNA Polymerases

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Translesion (TLS) polymerases rescue stalled DNA polymerases at sites of damaged bases by replacing the replicative polymerase and installing a nucleotide across the damaged site. Doing so, TLS allows additional time for the cell to repair the damage before resuming regular DNA replication.
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DNA replication is initiated at sites containing predefined DNA sequences known as origins of replication. DNA is unwound at these sites by the minichromosome maintenance (MCM) helicase and other factors such as Cdc45 and the associated GINS complex.The unwound single strands are protected by replication protein A (RPA) until DNA polymerase starts synthesizing DNA at the 5’ end of the strand in the same direction as the replication fork. To prevent the replication fork from falling apart,...
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Updated: Feb 14, 2026

Lesion Explorer: A Video-guided, Standardized Protocol for Accurate and Reliable MRI-derived Volumetrics in Alzheimer's Disease and Normal Elderly
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Elderly man with a right atrioventricular ring lesion

Yifei Gai1, Jun Yang2,3, Tan Li2,3

  • 1Department of Cardiovascular Ultrasound, The First Hospital of China Medical University, Shenyang, China.

Heart (British Cardiac Society)
|February 12, 2026
PubMed
Summary

No abstract available in PubMed .

Keywords:
Coronary VesselsEchocardiography

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