In-Depth Analysis of the Prognostic Factors Associated with Short-Term Outcome in Equine Colic Patients: Multicentric
Irene Nocera1, Dania Cingottini1, Chiara Di Franco1
1Department of Veterinary Science, University of Pisa, Viale delle Piagge 2, 56122 Pisa, Italy.
Animals : an Open Access Journal From MDPI
|February 13, 2026
Summary
Equine colic prognosis is complex, with older horses and specific colic types indicating poorer outcomes. Identifying risk factors like age and colic type is crucial for better equine colic management and treatment strategies.
Area of Science:
- Veterinary Medicine
- Equine Science
- Animal Health
Background:
- Colic is a common cause of equine morbidity and mortality.
- Previous studies on risk and prognostic factors for equine colic have yielded debated consensus.
- Identifying reliable prognostic indicators is essential for clinical decision-making.
Purpose of the Study:
- To investigate colic outcomes in horses referred to equine centers.
- To identify specific risk factors associated with negative colic outcomes in equids.
- To contribute to a clearer understanding of equine colic prognosis.
Main Methods:
- A multicenter retrospective study analyzing 236 equine clinical records.
- Data collected included history, signalment, physical examination, hematology, biochemistry, diagnosis, SIRS status/score, colic type, treatment, and outcome.
- Multivariable logistic regression was used to assess parameters associated with colic outcomes (p < 0.05).
Main Results:
- Age and colic type were significantly associated with negative outcomes (p < 0.001 for both).
- Univariate analysis suggested potential associations with sex, treatment type, SIRS score, age, heart rate, and respiratory rate.
- Poor outcomes correlated with advanced age, strangulating obstructive colic, elevated heart rate, SIRS status, and blood lactate levels.
Conclusions:
- Equine colic risk is multifactorial, with age and specific colic types being key prognostic indicators.
- Cardiovascular signs, SIRS status, and elevated lactate are linked to poorer colic outcomes.
- A multicenter approach with standardized protocols enhances the robustness and representativeness of findings in equine colic research.
More Related Videos
Related Concept Videos
Factors Affecting Protein-Drug Binding: Patient-Related Factors
340
Protein-drug binding, a pivotal aspect of pharmacokinetics, is subject to considerable variability influenced by an array of patient-related factors. The intricate interplay of age, individual differences, and pathological conditions significantly impact the binding dynamics and subsequent pharmacological effects.
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
340
Predicting Reaction Outcomes
11.0K
Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
11.0K
Outcomes of Glycolysis
107.8K
Nearly all the energy used by cells comes from the bonds that make up complex organic compounds. These organic compounds are broken down into simpler molecules, such as glucose. As a result, cells extract energy from glucose over many chemical reactions—a process called cellular respiration.
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
107.8K
Long-term Depression
33.4K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.4K
Uniform Depth Channel Flow
619
Uniform depth channel flow keeps fluid depth consistent along channels such as irrigation canals. In natural channels, such as rivers, approximate uniform flow is often assumed. This condition occurs when the channel’s bottom slope matches the energy slope, balancing potential energy lost from gravity with head loss due to shear stress. This balance prevents depth changes along the channel length, resulting in a steady, uniform flow.Uniform flow in open channels with a constant cross-section...
619
Depth Perception and Spatial Vision
2.1K
Depth perception is the ability to perceive objects three-dimensionally. It relies on two types of cues: binocular and monocular. Binocular cues depend on the combination of images from both eyes and how the eyes work together. Since the eyes are in slightly different positions, each eye captures a slightly different image. This disparity between images, known as binocular disparity, helps the brain interpret depth. When the brain compares these images, it determines the distance to an object.
2.1K


