Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Relative Risk01:12

Relative Risk

2.2K
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.2K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

13.9K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.9K
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

2
Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
2
Design Example: Analyzing Capacity Contours for Flood Risk Assessment01:17

Design Example: Analyzing Capacity Contours for Flood Risk Assessment

334
Flood risk assessment involves careful planning and analysis to ensure the safety of communities near water retention structures. Capacity contours are a vital tool in this process, as they illustrate the potential spread of water at specific levels in a given area. In the context of building a bund across a small valley, these contours play a critical role in evaluating the safety of nearby residential areas.In this example, the bund is intended to store stormwater in the valley. The engineers...
334
Molecular Models02:00

Molecular Models

43.9K
Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.
43.9K
The Bohr Model02:18

The Bohr Model

81.1K
Following the work of Ernest Rutherford and his colleagues in the early twentieth century, the picture of atoms consisting of tiny dense nuclei surrounded by lighter and even tinier electrons continually moving about the nucleus was well established. This picture was called the planetary model since it pictured the atom as a miniature “solar system” with the electrons orbiting the nucleus like planets orbiting the sun. The simplest atom is hydrogen, consisting of a single proton as the...
81.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Textbook outcome in surgery for primary hyperparathyroidism: first steps toward a composite quality metric.

Updates in surgery·2026
Same author

Pro-regenerative fingerprints identified in a sub-population of adult mouse cardiomyocytes by integrative single-cell proteomics.

Genome biology·2026
Same author

Development and initial validation of a hierarchically structured multidimensional scale of quality of working life.

Frontiers in psychology·2026
Same author

An audit of the PeptideAtlas database uncovers evidence for repurposed pseudogenes and co-opted retroviral ORFs.

BMC genomics·2025
Same author

Impact of parathyroidectomy on depression symptoms in patients with primary hyperparathyroidism: A systematic review and meta-analysis.

Surgery·2025
Same author

The Influence of the Clinical, Therapeutic and Socio-Personal Profile on the Quality of Life of Patients With Multiple Endocrine Neoplasia Type 1.

World journal of surgery·2025

Related Experiment Video

Updated: Feb 14, 2026

An R-Based Landscape Validation of a Competing Risk Model
05:37

An R-Based Landscape Validation of a Competing Risk Model

Published on: September 16, 2022

2.6K

Symptomatic Pheochromocytoma: A Risk Model.

María Consuelo Muñoz1, Beatriz Febrero2,3,4, Miriam Abellán2

  • 1Hospital Comarcal del Noroeste, 30400 Murcia, Spain.

Cancers
|February 13, 2026
PubMed
Summary

Symptomatic pheochromocytoma (PHEO) is linked to sex, genetics, and hormone profile, increasing perioperative risks. A predictive nomogram aids in managing patients with this rare tumor.

Keywords:
Pheochromocytomarisk modelsymptoms

More Related Videos

Establishing a Competing Risk Regression Nomogram Model for Survival Data
04:57

Establishing a Competing Risk Regression Nomogram Model for Survival Data

Published on: October 23, 2020

10.9K
Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

88.1K

Related Experiment Videos

Last Updated: Feb 14, 2026

An R-Based Landscape Validation of a Competing Risk Model
05:37

An R-Based Landscape Validation of a Competing Risk Model

Published on: September 16, 2022

2.6K
Establishing a Competing Risk Regression Nomogram Model for Survival Data
04:57

Establishing a Competing Risk Regression Nomogram Model for Survival Data

Published on: October 23, 2020

10.9K
Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

88.1K

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Genetics

Background:

  • Pheochromocytoma (PHEO) diagnosis is increasing via incidental findings and genetic screening.
  • Predictors of symptomatic PHEO presentation and associated perioperative risks are not well-defined.

Purpose of the Study:

  • Quantify symptomatic PHEO prevalence.
  • Identify factors associated with symptomatic presentation.
  • Compare perioperative outcomes between symptomatic and asymptomatic PHEO.
  • Develop a predictive nomogram for symptomatic PHEO risk.

Main Methods:

  • Retrospective analysis of 173 PHEO patients (1984-2021).
  • Logistic regression to assess associations with symptomatic presentation.
  • Nomogram construction and evaluation using ROC analysis (AUC).

Main Results:

  • 67.1% of patients were symptomatic.
  • Male sex and germline mutations decreased symptom likelihood; noradrenergic profile increased it.
  • Symptomatic PHEO correlated with higher intraoperative and postoperative complication rates.
  • The nomogram showed moderate predictive discrimination (AUC 0.799).

Conclusions:

  • Symptomatic PHEO presentation is influenced by sex, genetic status, and secretion profile.
  • Symptomatic PHEO is associated with increased perioperative morbidity.
  • A predictive nomogram using available variables can aid risk assessment and perioperative management.