Related Experiment Video
Updated: Feb 14, 2026

Tear-Derived Exosomal miR-15a as New Diagnostic Tool for Diabetic Retinopathy
Published on: December 30, 2025
Diabetic Retinopathy Screening in Primary Care Real Practice: Study Procedures and Baseline Characteristics from the
Víctor-Miguel López-Lifante1,2,3,4,5, Maria Palau-Antoja1, Noemí Lamonja-Vicente1,6
1Unitat de Suport a la Recerca Metropolitana Nord, Institut Universitari d'Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), 08303 Mataró, Spain.
Early diabetic retinopathy (DR) detection is vital. This study assesses agreement between primary care physicians, ophthalmologists, and AI in DR screening and referral, aiming to improve early detection in primary care settings.
Area of Science:
- Ophthalmology
- Primary Care Medicine
- Artificial Intelligence
Background:
- Rising diabetes rates necessitate early detection of diabetic retinopathy (DR), a major cause of vision loss.
- Integrating DR screening into primary care settings shows promise for improved patient outcomes.
- Technological advancements, including AI, offer potential to enhance DR screening processes.
Purpose of the Study:
- To evaluate the agreement among primary care physicians (PCPs), ophthalmologists, and an AI system in DR screening.
- To assess the concordance of referral decisions for DR made by PCPs, ophthalmologists, and AI.
- To investigate the feasibility of implementing AI-assisted DR screening within a real-world primary care environment.
Main Methods:
- Retrospective collection of 1517 retinographies from 301 diabetic patients using a non-mydriatic retinal camera.
- Analysis of DR screening and referral decisions made by PCPs.
- Comparison of PCP decisions with ophthalmologist and AI-based assessments (planned for future analysis).
Main Results:
- Primary care physicians referred 34.5% of patients for ophthalmological evaluation.
- Referrals were primarily for suspected DR, retinal diseases, or media opacification.
- 13.62% of participants were suspected of having DR, with 9.63% receiving a confirmed diagnosis.
Conclusions:
- Initial findings highlight the role of PCPs in DR screening and referral.
- Further analysis will determine concordance between PCPs, AI, and ophthalmologists.
- Results are expected to support the integration of effective DR screening strategies into clinical practice.
More Related Videos
Related Concept Videos
Characteristics of Practical Op Amps
The ratio of differential gain to the common-mode gain is defined as the common-mode rejection ratio (CMRR). This ratio quantifies the ability of operational amplifiers (op-amps) to reject common-mode...
Tracheostomy Care II: Procedure
Step 1: Perform hand hygiene, and put on personal protective equipment: gown, gloves, mask...
Tracheostomy Care I: Pre-procedural Steps
Required Equipment
The equipment necessary for tracheostomy care includes:
Characteristics of Life
Fischer Projections
Newman Projections
The organic molecules rotate across the single bonds leading to numerous temporary three-dimensional structures of varying energy known as...

