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The Psychological Impact of In Vitro Fertilization (IVF): A Gender Systematic Review
Maria Grammenou1, Vasiliki Michou1, Aikaterini Itziou1
1Department of Midwifery, School of Healthcare Sciences, University of Western Macedonia, Keptse, 50200 Ptolemaida, Greece.
Healthcare (Basel, Switzerland)
|February 13, 2026
Summary
In Vitro Fertilization (IVF) treatment causes psychological distress, including anxiety and depression, in both men and women. Women generally experience higher distress levels than men throughout the IVF process.
Area of Science:
- Reproductive Medicine
- Psychology
- Infertility Studies
Background:
- In Vitro Fertilization (IVF) offers hope for infertility but has psychological implications.
- The emotional impact of IVF treatment can differ significantly between genders.
Purpose of the Study:
- To systematically review the literature on the psychological impact of IVF.
- To explore gender-specific emotional responses to IVF treatment.
Main Methods:
- Systematic literature search conducted across multiple databases.
- Inclusion of studies published in English between 2000 and 2023.
Main Results:
- 47 studies analyzed the psychological effects of IVF on men and women.
- Both genders experience anxiety, depression, and reduced quality of life during IVF.
- Women reported higher levels of psychological distress, including anxiety and depression, compared to men.
Conclusions:
- Recognizing gender-specific psychological responses is vital for effective IVF support.
- Targeted interventions can improve mental well-being for individuals undergoing IVF.
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