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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

504
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
504
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

449
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
449
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

410
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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Viral Recombination00:57

Viral Recombination

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Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
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Kidney Structure01:45

Kidney Structure

75.5K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
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Viral Structure00:56

Viral Structure

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Viruses are extraordinarily diverse in shape and size, but they all have several structural features in common. All viruses have a core that contains a DNA- or RNA-based genome. The core is surrounded by a protective coat of proteins called the capsid. The capsid is composed of subunits called capsomeres. The capsid and genome-containing core are together known as the nucleocapsid.
74.8K

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Impact of older donor age in kidney transplants in a biopsy-based observational study.

JCI insight·2026
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Corrigendum to "Improving the histologic detection of donor-specific antibody-negative antibody-mediated rejection in kidney transplants" [American Journal of Transplantation Volume 26, Issue 1, January 2026, Pages 117-130].

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Xenotransplantation in Nephrology: A Narrative Review.

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Updates in the Diagnosis and Treatment of BK Viraemia in Kidney Transplant Recipients: Current and Future Insights.

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Transforming Dialysis Access Together Dialysis Access Training: Recommendations for Nephrology Fellows.

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Related Experiment Video

Updated: Feb 14, 2026

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
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TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients

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Viral Infections in Kidney Transplant Recipients: Current Practice and Updates.

Kayinsola Kehinde Babatunde1, Donnchadh Reidy1, Dearbhail Ni Cathain1

  • 1Department of Nephrology, St. Vincent's University Hospital, D04 T6F4 Dublin, Ireland.

Journal of Clinical Medicine
|February 13, 2026
PubMed
Summary

Viral infections pose significant risks to kidney transplant recipients, impacting graft function and survival. This review highlights key viruses, challenges in diagnosis and treatment, and the need for improved screening strategies.

Keywords:
immunosuppressionkidney transplantationviral infections

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Area of Science:

  • Nephrology
  • Infectious Diseases
  • Transplantation Immunology

Background:

  • Kidney transplantation is the optimal treatment for end-stage kidney disease.
  • Historically, focus was on rejection, but viral infections are now major causes of morbidity and mortality in immunosuppressed patients.
  • Viruses significantly impact kidney graft function and patient outcomes globally.

Purpose of the Study:

  • To review the epidemiology, diagnostics, screening, and treatment of key viruses affecting kidney transplant recipients.
  • To discuss challenges including shifting viral epidemiology, antimicrobial resistance, and virus-associated malignancies.
  • To highlight the need for improved screening assays for donors and recipients.

Main Methods:

  • Literature review of articles from the PubMed database.
  • Search terms included kidney transplantation and infectious diseases.
  • Focus on viruses such as cytomegalovirus, polyoma virus, Epstein-Barr virus, and others.

Main Results:

  • Identified key viruses impacting kidney transplant recipients and their implications.
  • Examined differences in viral epidemiology, diagnostic challenges, and available treatments.
  • Highlighted emerging viral threats and the complexities of managing viral infections.

Conclusions:

  • Viral infections are a critical concern in kidney transplant recipients, necessitating careful management.
  • International collaboration is needed to address challenges like global mobility's impact on viral epidemiology and antimicrobial resistance.
  • Development of superior screening methods for donors and recipients is essential for better outcomes.